Product Details:Humalog Mix 25
Contents Insulin lispro, insulin lispro protamine (rDNA origin). Indications Treatment of patients with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis.Dosage Administration The dosage should be determined by the physician, according to the requirement of the patient. Humalog Mix 25 may be given shortly before meals. When necessary, Humalog Mix 25 can be given soon after meals. Humalog Mix 25 should only be given by SC injection. Under no circumstances should Humalog Mix 25 be given IV. SC administration should be in the upper arms, thighs, buttocks or abdomen. Use of injection sites should be rotated so that the same site is not used more than approximately once a month. When administered SC, care should be taken when injecting Humalog Mix 25 to ensure that a blood vessel has not been entered. After injection, the injection site should not be massaged. Patients must be educated to use the proper injection techniques. The rapid onset and early peak of Humalog activity itself is observed following the SC administration of Humalog Mix 25. This allows Humalog Mix 25 to be given very close to mealtime. The duration of action of the insulin lispro protamine suspension (NPL) component of Humalog Mix 25 is similar to that of a basal insulin NPH.
The time course of action of any insulin may vary considerably in different individuals or at different times in the same individual. As with all insulin preparations, the duration of action of Humalog Mix 25 is dependent on dose, injection site, blood supply, temperature and physical activity.